Tuesday, February 11, 2014

You Can Now Measure Forced Expiration in Rats

SCIREQ's flexiVent negative pressure-driven forced expiration (NPFE) extension is now available for rats! Like previously reported in mice1, this extension offers the possibility to perform refined forced expiration measurements in a wider range of laboratory animals. This is done through the unique combination of the NPFE technique with the traditional forced oscillation (FO) measurements of the flexiVent in a single set-up.

Forced Expired Volume (FEV) is a widely accepted spirometry outcome in clinical settings. SCIREQ's new NPFE extension for rats now expands the measurement range available in that species with forced expiration parameters that resemble those obtained in humans like FEV, forced expired flow (FEFx), forced vital capacity (FVC) or peak expiratory flow (PEF).

Click here to read about this technique.


We are pleased to announce that the rat NPFE extension is currently available for the flexiVent FX and that it allows for combined NPFE and FOT measurements.

Rat NPFE extension specifications:

  • Used with flexiVent FX module 4
  • Suitable for rats from 150g - 300g
  • Chamber size: approximately 8" long x 4" in diameter
  • Contact our team to find out more about this new application and how to receive your own: [email protected] or toll-free at 1.877.572.4737.

    1Shalaby et al. 2010. Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness. Respir Res 11:82

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