The overarching goal of the CounterACT program is to integrate cutting-edge research with the latest technological advances in science and medicine for a more rapid and effective response during chemical emergencies. When studying chemical threats it is important to understand the effect of the agent itself but also the potential effects of any therapeutic countermeasure. The respiratory system in particular is often affected due to the inhaled nature of these threats.
The flexiVent is an integrated platform that combines a computer-controlled piston ventilator with advanced lung modelling capabilities. It automates the collection, analysis and plotting of pulmonary mechanics data to provide in-depth lung function measurements.
The flexiVent has been used in a wide range of applications focused on vesicant induced lung injury (chlorine, sarin, mustard, etc.). Its unique ability to measure central vs. peripheral airways, combined with delivered dose estimators and automated dose-response feature permit unique and novel insights into inflammatory responses and evolution of lung injury throughout the progression of an exposure.
Publications featuring the flexiVent
The inExpose is a compact and customizable inhalation exposure system, which can be used for nose-only or whole body exposures in a range of subjects. It provides a reproducible way of exposing animals to a test atmosphere, creating relevant and practical animal models.
The inExpose caters to a vast number of inhalation research applications, ranging from developing an infectious disease model to testing a therapeutic delivery system.
Publications featuring the inExpose
Stop by to learn more about our full suite of pulmonary products and how they may be beneficial for your research!
Join us in New York
Join us at the 9th Annual NIH Countermeasures Against Chemical Threats (CounterACT) Network Research Symposium in New York City from June 15th to 17th:
Monday June 15 - 7:30am to 7:00pm
Tuesday June 16 - 7:30am to 6:00pm
Wednesday June 17 - 7:30am to 3:00pm
Phone 1.514.286.1429 | Toll Free 1.877.572.4737