We are pleased to announce the publication of our first video article in the Journal of Visualized Experiments (JoVE). "[...] JoVE is a peer reviewed, PubMed indexed journal devoted to the publication of biological, medical, chemical and physical research in a video format."1
The article, which was produced in collaboration with the Meakins-Christie Laboratories of McGill University, illustrates and describes the steps to perform forced oscillation measurements in mice using the flexiVent. It includes the procedure to adequately prepare the system, tracheotomize, cannulate and mechanically ventilate a mouse, as well as to record lung function measurements. In addition, typical results at baseline and following aerosolized methacholine challenges are presented and discussed.
We invite you to watch the video and to read the article for additional details.
Evaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique
1JoVE - Peer Reviewed Scientific Video Journal - Methods and Protocols MyJoVE Corp. 2006-2013. < http://www.jove.com/about >.