Monday, December 16, 2013

Happy holidays from SCIREQ

Please note that SCIREQ offices will be closed during the holidays. Our last day is Tuesday December 24, 2013 with limited staff available, and we will be back hard at work on Thursday January 2, 2014.

Should you have any questions before then, we would be happy to assist you.

All of us at SCIREQ wish you a joyful holiday season along with health and success in the New Year!

Monday, December 9, 2013

Continuing to refine the Dose Response

Our team continuously works to ensure that the flexiVent provides the most accurate and reproducible data. Our latest software development, flexiWare 7.5, introduces a major refinement to dose response data. The software estimates the dose delivered to the subject and automatically generates a dose response curve. Plotting against delivered dose, rather than concentration, standardizes the collected data. This also allows for accurate comparisons between groups using different equipment or nebulization protocols.

Since the release of flexiWare 7.5, we have continued to refine the dose response. Our most recent improvement allows for characterization of losses due to rain-out when calculating the dose delivered to the subject. By characterizing individual configurations, we are able to determine the fraction of nebulized compound that reaches the subject during nebulization. With all of these refinements, we continue to bring further accuracy and reproducibility to typical dose response studies.

Want to get this feature? Purchase our latest software and become eligible for free software upgrades for a whole year! Contact our team at [email protected].

Wednesday, November 27, 2013

Happy American Thanksgiving!

The Canadian SCIREQ team wishes all its American customers a very happy Thanksgiving! May you spend fun times with family and friends - enjoy the celebrations!

Please note that our Canadian office will be open during this time.

Friday, November 8, 2013

How SCIREQ helps you apply for grants

Are you in the process of preparing a grant application to initiate or expand your research? Our team is happy to provide information, quotations and references for inclusion in the proposal. Contact us at [email protected] to request the details you need to submit in time for your deadline.

We look forward to hearing from you and hope the best for your application!

Friday, October 25, 2013

Upper airway resistance measurements with the flexiVent

While the flexiVent is typically utilized to assess the mechanical properties of the lower airways, it can also be used for accurate measurements of nasal obstruction. As previously reported in respected scientific journals1-3, this approach provides a means to reliably and directly assess upper airway resistance in disease models.


Similar to respiratory mechanics measurements of the lower airways, the flexiVent uses the forced oscillation technique to deliver a small amplitude test signal to the upper airways. Nasal resistance is then derived by the operating software from the pressure-flow relationship as described in the Single Compartment Model. At the moment, these measurements are described in allergic rhinitis pre-clinical research, one of the most common allergic diseases worldwide affecting people of all ages.

Our customer service team is happy to provide additional details or discuss how these measurements may compliment your research application. We invite you to contact us at [email protected] for further information.

Read more

1. McLeod et al. J Pharmacol Tox Methods 48: 153, 2002
2. Miyahara et al. J All Clin Immunol 116: 1020, 2005
3. Miyahara et al. J All Clin Immunol 121: 718, 2008

Monday, October 21, 2013

Happy Respiratory Care week!

It's Respiratory Care week! Thank you RRTs and all of those involved in Respiratory Care! Take time this week to spread awareness, support people living with respiratory conditions and educate yourself about preventive measures.

Read more at the AARC website:

Friday, October 11, 2013

Happy Canadian Thanksgiving!

We would like to wish a Happy Thanksgiving to all our Canadian customers and colleagues. May you all have a wonderful long weekend with your family and friends.

Please note that our Montreal office will be closed on Monday October 14th for this holiday. Our SCIREQ USA office will remain open and you can reach us at 514.286.1429 or 877.572.4737 (toll-free in Canada & US) or by email at [email protected] and [email protected].

Wednesday, October 9, 2013

Are e-cigarettes safe?

"E-cigarettes have become a billion dollar industry, with one in five North Americans trying the product1". However, the question of how safe the battery operated devices are still remains unanswered even a decade after the product entered the market. The main reason for that is that there is insufficient research available to conclusively determine its long term safety on the user and environment. That situation could however change since researchers can now effectively and reproducibly study the impacts of e-cigarettes using the inExpose system.

inExpose Application

E-cigarettes of various dimensions can easily be integrated to the inExpose system to generate and deliver an unparalleled number of reproducible exposure profiles applicable to in vitro as well as in vivo studies. We invite you to watch the video below that showcases, from generation to delivery site, an example of how exposure to e-cigarette mist could be experimentally conducted.

The inExpose system is a computer-controlled, compact inhalation exposure system that offers turnkey solutions for aerosols, cigarette smoke, atmospheric pollutants or test compounds. It features a low-internal volume construction to minimize unintentional dilutions, thereby allowing for rapid achievements and changes of desired test atmosphere concentrations.

To find out how the inExpose can help you advance your research, please contact one of our dedicated team members toll free at +1.877.572.4737 or by email at [email protected] .

1Hermiston, & Steele (2013). How safe are e-cigarettes? CTV British Columbia Retrieved from

Friday, September 27, 2013

Great workshop in Bar Harbor!

As in the past, the Phenotyping Mouse Models of Human Lung Disease Workshop organized by The Jackson Laboratory attracted an international group of participants and presenters. Theoretical and hands-on laboratory sessions directed at accurate respiratory mechanics measurements using the forced oscillation techniques covered an important part of the workshop. This was complemented by other techniques employed to study human pulmonary diseases using mouse models.

The cordial format of the workshop permitted direct, one-on-one interactions with presenters and instructors. Participants also had an opportunity to get first-hand experience working with the flexiVent system while learning how to gather even more pertinent data for their research.

We are already looking forward to the next workshop. Join us next time!

Wednesday, September 11, 2013

Thank you ERS!

The SCIREQ team once again has enjoyed participating in the European Respiratoy Society's Annual Congress in Barcelona. Our partnership with our distributor EMKA Technologies was strengthened as we presented the flexiVent and inExpose systems in a joint booth.

It was a pleasure to see our international users come by the booth to discuss their research topics and experiences with our equipment. We always enjoy the opportunity to exchange ideas with our customers to learn about their applications while offering the best solutions for accurate respiratory mechanics measurements and inhalation exposure.

Friday, September 6, 2013

Participate in a hands-on workshop at the Jackson Laboratory in Bar Habor

Our very own Senior Scientsist, Dr. Annette Robichaud will again be presenting at this years Jackson Lab workshop on Phenotyping Mouse Models of Human Lung Disease from September 15th to 20th. This workshop is an excellent opportunity to acquire hands-on training in respiratory mechanics measurements using the flexiVent as well as to learn from various experts in the field.

2013 Speakers include:
Jennifer Corrigan, M.S., The Jackson Laboratory
Kristin Cough, B.S., The Jackson Laboratory
Eric A. Hoffman, Ph.D., University of Iowa Carver College of Medicine
James J. Lee, Ph.D., Mayo Clinic Arizona
Lennart K.A. Lundblad, Ph.D., University of Vermont
John Macauley, Ph.D., The Jackson Laboratory
Frank McKeon, Ph.D., The Jackson Laboratory for Genomic Medicine
Wayne Mitzner, Ph.D., Johns Hopkins Bloomberg School of Public Health
Matthias Ochs, M.D., Hannover Medical School
Annette Robichaud, Ph.D., SCIREQ Scientific Respiratory Equipment, Inc.
Teresa Southard, D.V.M., Ph.D., Cornell University
Marge Strobel, Ph.D., The Jackson Laboratory
Douglas Taatjes, Ph.D., The University of Vermont
Jerrold Ward, DVM, Ph.D., Global VetPathology and NIAID, NIH
Wa Xian, Ph.D., The Jackson Laboratory for Genomic Medicine

Space still available, click here to register today!

Wednesday, August 28, 2013

Exhibiting in Barcelona: ERS Annual Congress 2013

At this year's ERS Annual Congress at the Fira Barcelona Convention Centre, we are looking forward to continuing to build our close relationship and exhibiting alongside our European distributor emka TECHNOLOGIES. We invite you to come by booth G11 and see the latest developments of our flexiVent FX as well as our inhalation exposure system the inExpose.

Monday, August 19, 2013

Join the SCIREQ team: We're Hiring!

We are looking for an enthusiastic, motivated individual with an interdisciplinary background combining technical and engineering skills with life sciences to join our Sales and Technical Support team for our line of high-tech pulmonary research devices.

Our group is composed of multi-disciplinary individuals who work together collaboratively to be at the forefront of science and innovation in our field. We offer a wide variety of responsibilities and challenges, a friendly team environment, exciting growth opportunities and a pleasant, modern working environment.

If you are interested in joining us, please consult our current job posting: Product Specialist.

Monday, August 5, 2013

Visit from MediAnalytika

For us at SCIREQ it is not only important to keep in close contact with our customers, but also with our distributors! Most recently we had the great pleasure to welcome our Indian distributors over several days at our head office in Montreal. Each meeting with our distributors provides a great opportunity for an exchange of ideas, in depth product discussion and an opportunity to strengthen our collaboration. We enjoyed having Mr. Ramesh and Mr. Sathya assist our product demonstrations and participate in our applications discussions. At the same time it was very interesting for our team to learn about business customs in India.

We offer a wide network of distribution for both our flexiVent and inExpose systems. All our distributors are available to address your questions and meet your research needs. To find the distributor in your area, please visit our website and search with our distributor locator.

Monday, July 22, 2013

Learn how the inExpose can help refine your experiments

A compilation of recent publications featuring our inhalation exposure system, the inExpose, was recently brought together into an Application Note.

Reading through this note, you will gain a better understanding of how and where our system was used, including cigarette smoke, aerosol, air pollutant exposures, etc. Like the flexiVent, the inExpose is a sophisticated, precision scientific instrument that can bring additional standardization to critical intervention processes. As exemplified in this Application Note, both instruments can even be used in combination to address various research questions.

Click here to download the Application Note and learn how you could positively impact your research reproducibility and efficiency.

Fahmy et al. Environ Toxicol Pharmacol 29: 173, 2010 (with permission).

Monday, July 8, 2013

Are you using the full power of your flexiVent?

A recent book chapter by Dr. J.M. Hartney and SCIREQ's own Senior Scientist Dr. Annette Robichaud features airway hyperresponsiveness assessment in mice using detailed measurements respiratory mechanics.

The chapter, published in Methods in Molecular Biology1, respects the 30 year tradition of the well-known book series of providing detailed step-by-step protocols supplemented by notes offering protocol related advice or tips.

While this article is primarily directed at researchers new to the field of respiratory mechanics, we invite anyone interested in airway hyperresponsiveness or detailed measurements of respiratory mechanics to read it. Click the book cover image for full details.

1Edited by Irving C. Allen, Mouse Models of Allergic Disease, Methods and Protocols.


We are proud of this contribution and want to offer the possibility to the 10 first readers of this blog to get a free copy of this book. To enter the contest, simply e-mail us your name, organization name and mailing address at [email protected].

Wednesday, June 26, 2013


We are pleased to announce the publication of our first video article in the Journal of Visualized Experiments (JoVE). "[...] JoVE is a peer reviewed, PubMed indexed journal devoted to the publication of biological, medical, chemical and physical research in a video format."1

The article, which was produced in collaboration with the Meakins-Christie Laboratories of McGill University, illustrates and describes the steps to perform forced oscillation measurements in mice using the flexiVent. It includes the procedure to adequately prepare the system, tracheotomize, cannulate and mechanically ventilate a mouse, as well as to record lung function measurements. In addition, typical results at baseline and following aerosolized methacholine challenges are presented and discussed.

We invite you to watch the video and to read the article for additional details.

Evaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique

1JoVE - Peer Reviewed Scientific Video Journal - Methods and Protocols MyJoVE Corp. 2006-2013. < >.

Tuesday, June 4, 2013

Thank you for coming by our booth at ATS

We have been attending ATS for over 15 years and this year our team was present again to demonstrate our products and discuss with exhibit hall visitors. We were very pleased to see familiar faces from all over the world but also met many new researchers and scientists. We made the most out of our time in Philadelphia by presenting two posters and hosting the Breakfast Symposium: Refining the Dose Response while also attending sessions.

If you didn't get the chance to stop by our posters, please take a look by clicking on the title below to download each one.

Mechanical Test Load Comparative Study of Three FlexiVent System Configurations

Raised-Volume Low Frequency Forced Oscillation Measurements Of Respiratory Mechanics In Conscious And Anaesthetized Mice

A big thank you to the show organizers and everyone we met. We look forward to continuing the conversation!

Friday, April 26, 2013

Boston events were a great success!

Our SCIREQ team was in Boston the week of April 21st exhibiting at Experimental Biology and hosting our very own flexiVent User Group Meeting. Both events were a great success as we were able to meet many new people and spend some quality time with our customers.

flexiVent User Group Meeting

We had over 15 flexiVent users join us on April 24th to discuss new flexiVent FX developments, new software features, frequently asked questions and even hear from select users on their current research. It was a great opportunity to meet new users and catch up with our flexiVent veterans.

Thank you to everyone who attended.

Keep an eye out for our next User Group Meeting in your area! We will be holding this event on a regular basis and would like your input if you are interest in having one in your area.

Thursday, April 18, 2013

Boston meetings to proceed as scheduled

All of us at SCIREQ would like to express our shock and horror at the atrocious events that took place at the Boston Marathon last Monday. Our hearts go out to the victims, their families and all those affected.

Experimental Biology

As per the information currently available to us, the exhibit at the Experimental Biology conference is set to proceed as scheduled. Further information can be found on the EB website.

The exhibit is located at the Boston Convention and Exhibition Center and is open April 21 to 23 from 9 am to 4 pm. Our SCIREQ team will be happy to welcome you at booth #446.

flexiVent User Group Meeting

The flexiVent User Group Meeting is scheduled for Wednesday, April 24, at the Westin Copley Plaza hotel. We have confirmed the continued availability and security of this venue with the hotel staff, therefore this meeting will also proceed as scheduled.

We understand that the proximity of our venue to the site of the attacks may cause discomfort to some of our attendees. However, after thorough consideration, we feel that the meeting should go ahead at this site as we refuse, whenever possible, to allow such events to change the way we live our lives. We hope that our attendees and clients agree with this choice, and that attendance at the User Group Meeting will be unattenuated.

For further information about the User Group Meeting, please refer to this earlier posting. To register, please fill in our online form.

We look forward to seeing you in Boston!

Friday, April 5, 2013

Visit us at CRC in Quebec City

If you are going to attend the Canadian Respiratory Conference in Quebec City from April 11 to 13, we invite you to come by the exhibits to talk to us and learn more about the latest flexiVent FX and inExpose developments. We will be sharing booth T7 with our sister company, THORASYS Thoracic Medical Systems Inc., makers of the tremoFlo Airwave Oscillometry System (AOS) to measure lung function without patient effort.

Canadian Respiratory Conference 2013
Quebec City Convention Center
April 11 - 13, 2013
Booth T7

Monday, March 18, 2013


Our team just returned from the Society of Toxicology's 52nd Annual Meeting in San Antonio and it was a great success! We would like to thank everyone who visited the SCIREQ booth to discuss current and potential applications for our inExpose and flexiVent FX systems.

We look forward to a further discussion at Experimental Biology in Boston. Join us at booth #446 from April 21-23.