Monday, December 16, 2013

Happy holidays from SCIREQ

Please note that SCIREQ offices will be closed during the holidays. Our last day is Tuesday December 24, 2013 with limited staff available, and we will be back hard at work on Thursday January 2, 2014.

Should you have any questions before then, we would be happy to assist you.

All of us at SCIREQ wish you a joyful holiday season along with health and success in the New Year!

Monday, December 9, 2013

Continuing to refine the Dose Response

Our team continuously works to ensure that the flexiVent provides the most accurate and reproducible data. Our latest software development, flexiWare 7.5, introduces a major refinement to dose response data. The software estimates the dose delivered to the subject and automatically generates a dose response curve. Plotting against delivered dose, rather than concentration, standardizes the collected data. This also allows for accurate comparisons between groups using different equipment or nebulization protocols.

Since the release of flexiWare 7.5, we have continued to refine the dose response. Our most recent improvement allows for characterization of losses due to rain-out when calculating the dose delivered to the subject. By characterizing individual configurations, we are able to determine the fraction of nebulized compound that reaches the subject during nebulization. With all of these refinements, we continue to bring further accuracy and reproducibility to typical dose response studies.

Want to get this feature? Purchase our latest software and become eligible for free software upgrades for a whole year! Contact our team at sales@scireq.com.

Wednesday, November 27, 2013

Happy American Thanksgiving!

The Canadian SCIREQ team wishes all its American customers a very happy Thanksgiving! May you spend fun times with family and friends - enjoy the celebrations!

Please note that our Canadian office will be open during this time.

Wednesday, November 20, 2013

Introduction to the MSX (Multi-Subject Extension) for flexiVent FX

One flexiVent, four subjects.

The MSX (Multi-Subject Extension) is designed for lung mechanics assessment in up to four anesthetized subjects in parallel. The MSX supplements the accurate lung mechanics measurements that are relied-on with the flexiVent with a high throughput system that will increase the efficiency of your studies.

We invite you to watch the Webinar below, recorded by our flexiVent product specialist, as an in depth introduction to the MSX. Enjoy!

Contact Us


If you have questions about the MSX or any of our SCIREQ products, please do not hesitate to contact our team.

Email: sales@scireq.com
Phone: Toll free (North America) 1.877.572.4737 or 514.286.1429

You can also visit our website to create your own TechNet account and gain access to a variety of flexiVent documentation.

Friday, November 8, 2013

How SCIREQ helps you apply for grants

Are you in the process of preparing a grant application to initiate or expand your research? Our team is happy to provide information, quotations and references for inclusion in the proposal. Contact us at sales@scireq.com to request the details you need to submit in time for your deadline.

We look forward to hearing from you and hope the best for your application!

Friday, October 25, 2013

Upper airway resistance measurements with the flexiVent

While the flexiVent is typically utilized to assess the mechanical properties of the lower airways, it can also be used for accurate measurements of nasal obstruction. As previously reported in respected scientific journals1-3, this approach provides a means to reliably and directly assess upper airway resistance in disease models.




How?

Similar to respiratory mechanics measurements of the lower airways, the flexiVent uses the forced oscillation technique to deliver a small amplitude test signal to the upper airways. Nasal resistance is then derived by the operating software from the pressure-flow relationship as described in the Single Compartment Model. At the moment, these measurements are described in allergic rhinitis pre-clinical research, one of the most common allergic diseases worldwide affecting people of all ages.

Our customer service team is happy to provide additional details or discuss how these measurements may compliment your research application. We invite you to contact us at sales@scireq.com for further information.

Read more

1. McLeod et al. J Pharmacol Tox Methods 48: 153, 2002
2. Miyahara et al. J All Clin Immunol 116: 1020, 2005
3. Miyahara et al. J All Clin Immunol 121: 718, 2008

Monday, October 21, 2013

Happy Respiratory Care week!

It's Respiratory Care week! Thank you RRTs and all of those involved in Respiratory Care! Take time this week to spread awareness, support people living with respiratory conditions and educate yourself about preventive measures.

Read more at the AARC website: www.aarc.org/rcweek.

Friday, October 11, 2013

Happy Canadian Thanksgiving!

We would like to wish a Happy Thanksgiving to all our Canadian customers and colleagues. May you all have a wonderful long weekend with your family and friends.

Please note that our Montreal office will be closed on Monday October 14th for this holiday. Our SCIREQ USA office will remain open and you can reach us at 514.286.1429 or 877.572.4737 (toll-free in Canada & US) or by email at sales@scireq.com and techsupport@scireq.com.

Wednesday, October 9, 2013

Are e-cigarettes safe?

"E-cigarettes have become a billion dollar industry, with one in five North Americans trying the product1". However, the question of how safe the battery operated devices are still remains unanswered even a decade after the product entered the market. The main reason for that is that there is insufficient research available to conclusively determine its long term safety on the user and environment. That situation could however change since researchers can now effectively and reproducibly study the impacts of e-cigarettes using the inExpose system.

inExpose Application

E-cigarettes of various dimensions can easily be integrated to the inExpose system to generate and deliver an unparalleled number of reproducible exposure profiles applicable to in vitro as well as in vivo studies. We invite you to watch the video below that showcases, from generation to delivery site, an example of how exposure to e-cigarette mist could be experimentally conducted.

The inExpose system is a computer-controlled, compact inhalation exposure system that offers turnkey solutions for aerosols, cigarette smoke, atmospheric pollutants or test compounds. It features a low-internal volume construction to minimize unintentional dilutions, thereby allowing for rapid achievements and changes of desired test atmosphere concentrations.

To find out how the inExpose can help you advance your research, please contact one of our dedicated team members toll free at +1.877.572.4737 or by email at sales@scireq.com .

1Hermiston, & Steele (2013). How safe are e-cigarettes? CTV British Columbia Retrieved from http://bc.ctvnews.ca/how-safe-are-e-cigarettes-1.1450448

Friday, September 27, 2013

Great workshop in Bar Harbor!

As in the past, the Phenotyping Mouse Models of Human Lung Disease Workshop organized by The Jackson Laboratory attracted an international group of participants and presenters. Theoretical and hands-on laboratory sessions directed at accurate respiratory mechanics measurements using the forced oscillation techniques covered an important part of the workshop. This was complemented by other techniques employed to study human pulmonary diseases using mouse models.

The cordial format of the workshop permitted direct, one-on-one interactions with presenters and instructors. Participants also had an opportunity to get first-hand experience working with the flexiVent system while learning how to gather even more pertinent data for their research.

We are already looking forward to the next workshop. Join us next time!

Wednesday, September 11, 2013

Software release: flexiWare 7.5.2

The latest version of our Study Management and Experiment Control Software, flexiWare 7.5.2 is a service pack structured to offer you the choice of having the new Dose Response View while also benefiting from an upgrade that adds several new and exciting features to the software.

What you get with flexiWare 7.5.2:

New! Multi-Subject Extension (MSX) Support
New! Dataset analyzers for transfer impedance
New! Cleaning Wizard
New! Pressure controlled ventilation
New! Controlled delivered volume
New! Optimal ventilator waveform (OVW) perturbations included for mice
New! Dose Response view (additional paid feature)
Improved flow channel calibration for FEV and MSX (flexiVent FX)
Seamless database updating to include default templates
Ability to change experiment database on the Welcome Dialog
Automatic migration of templates

DOSE RESPONSE VIEW

An automated dose response plot allows you to instantly visualize and export the meta-data for every parameter from every dose or intervention including the peak, mean, area under the curve, peak-to-peak among others. This time saving feature eliminates the need for lengthy post-experimental data processing and is available as an additional paid option. If you are interested in including this feature in your flexiWare software upgrade, please contact our sales team for a quote (1-877-572-4737 or sales@scireq.com).

MULTI-SUBJECT EXTENSION SUPPORT

flexiWare 7.5 now fully supports the new flexiVent Multi-Subject Extension (MSX) that permits studying up to four subjects simultaneously with a single flexiVent FX system. The software now seamlessly adapts ventilation and perturbation scaling as subjects are added or removed from the system, and new calibration methods and analyzers have been added to support the assessment of lung mechanics using transfer impedance.

VENTILATION ENHANCEMENTS

flexiWare 7.5 also introduces a number of enhancements to the control of mechanical ventilation for flexiVent users. We have added Pressure-Controlled Ventilation (PCV) as a new mode of ventilation that, when used with the MSX, allows standardization the inspiratory pressure across parallel subjects. For single-subject configurations, the software now offers a feature to control the delivered volume when using volume controlled ventilation patterns. This algorithm accounts for gas compression within the ventilator circuit to ensure that the subject is receiving the desired tidal volume with the best possible accuracy.

CONVENIENCE FEATURES

We listened to you and added more convenience features to this software version, little touches that equate to a better user experience and overall time saved. We have added a link on the Welcome Screen from which you can readily change your database connection. If you are upgrading from a previous software version, you will find that your templates are instantly converted to be compatible. In addition, any new databases that you create are automatically populated with our library of default templates. We assist you in the assignment of subjects to groups in the course of an experiment, you can now double click to zoom in on any data view panel and, finally, at the end of your experiments, you will find that you are led through the valve cleaning process by a step-by-step wizard.

HOW DO YOU UPGRADE?

If your current flexiWare installation is covered under our Complete Care program, our Technical Support team will be happy to assist you in downloading and installing your free upgrade. Otherwise, please contact our sales team at sales@scireq.com for further details and pricing information.

Thank you ERS!

The SCIREQ team once again has enjoyed participating in the European Respiratoy Society's Annual Congress in Barcelona. Our partnership with our distributor EMKA Technologies was strengthened as we presented the flexiVent and inExpose systems in a joint booth.

It was a pleasure to see our international users come by the booth to discuss their research topics and experiences with our equipment. We always enjoy the opportunity to exchange ideas with our customers to learn about their applications while offering the best solutions for accurate respiratory mechanics measurements and inhalation exposure.

Friday, September 6, 2013

Participate in a hands-on workshop at the Jackson Laboratory in Bar Habor

Our very own Senior Scientsist, Dr. Annette Robichaud will again be presenting at this years Jackson Lab workshop on Phenotyping Mouse Models of Human Lung Disease from September 15th to 20th. This workshop is an excellent opportunity to acquire hands-on training in respiratory mechanics measurements using the flexiVent as well as to learn from various experts in the field.

2013 Speakers include:
Jennifer Corrigan, M.S., The Jackson Laboratory
Kristin Cough, B.S., The Jackson Laboratory
Eric A. Hoffman, Ph.D., University of Iowa Carver College of Medicine
James J. Lee, Ph.D., Mayo Clinic Arizona
Lennart K.A. Lundblad, Ph.D., University of Vermont
John Macauley, Ph.D., The Jackson Laboratory
Frank McKeon, Ph.D., The Jackson Laboratory for Genomic Medicine
Wayne Mitzner, Ph.D., Johns Hopkins Bloomberg School of Public Health
Matthias Ochs, M.D., Hannover Medical School
Annette Robichaud, Ph.D., SCIREQ Scientific Respiratory Equipment, Inc.
Teresa Southard, D.V.M., Ph.D., Cornell University
Marge Strobel, Ph.D., The Jackson Laboratory
Douglas Taatjes, Ph.D., The University of Vermont
Jerrold Ward, DVM, Ph.D., Global VetPathology and NIAID, NIH
Wa Xian, Ph.D., The Jackson Laboratory for Genomic Medicine

Space still available, click here to register today!

Wednesday, August 28, 2013

Exhibiting in Barcelona: ERS Annual Congress 2013

At this year's ERS Annual Congress at the Fira Barcelona Convention Centre, we are looking forward to continuing to build our close relationship and exhibiting alongside our European distributor emka TECHNOLOGIES. We invite you to come by booth G11 and see the latest developments of our flexiVent FX as well as our inhalation exposure system the inExpose.

Monday, August 19, 2013

Join the SCIREQ team: We're Hiring!

We are looking for an enthusiastic, motivated individual with an interdisciplinary background combining technical and engineering skills with life sciences to join our Sales and Technical Support team for our line of high-tech pulmonary research devices.

Our group is composed of multi-disciplinary individuals who work together collaboratively to be at the forefront of science and innovation in our field. We offer a wide variety of responsibilities and challenges, a friendly team environment, exciting growth opportunities and a pleasant, modern working environment.

If you are interested in joining us, please consult our current job posting: Product Specialist.

Monday, August 5, 2013

Visit from MediAnalytika

For us at SCIREQ it is not only important to keep in close contact with our customers, but also with our distributors! Most recently we had the great pleasure to welcome our Indian distributors over several days at our head office in Montreal. Each meeting with our distributors provides a great opportunity for an exchange of ideas, in depth product discussion and an opportunity to strengthen our collaboration. We enjoyed having Mr. Ramesh and Mr. Sathya assist our product demonstrations and participate in our applications discussions. At the same time it was very interesting for our team to learn about business customs in India.


We offer a wide network of distribution for both our flexiVent and inExpose systems. All our distributors are available to address your questions and meet your research needs. To find the distributor in your area, please visit our website and search with our distributor locator.

Monday, July 22, 2013

Learn how the inExpose can help refine your experiments

A compilation of recent publications featuring our inhalation exposure system, the inExpose, was recently brought together into an Application Note.

Reading through this note, you will gain a better understanding of how and where our system was used, including cigarette smoke, aerosol, air pollutant exposures, etc. Like the flexiVent, the inExpose is a sophisticated, precision scientific instrument that can bring additional standardization to critical intervention processes. As exemplified in this Application Note, both instruments can even be used in combination to address various research questions.

Click here to download the Application Note and learn how you could positively impact your research reproducibility and efficiency.













Fahmy et al. Environ Toxicol Pharmacol 29: 173, 2010 (with permission).

Monday, July 8, 2013

Are you using the full power of your flexiVent?

A recent book chapter by Dr. J.M. Hartney and SCIREQ's own Senior Scientist Dr. Annette Robichaud features airway hyperresponsiveness assessment in mice using detailed measurements respiratory mechanics.

The chapter, published in Methods in Molecular Biology1, respects the 30 year tradition of the well-known book series of providing detailed step-by-step protocols supplemented by notes offering protocol related advice or tips.

While this article is primarily directed at researchers new to the field of respiratory mechanics, we invite anyone interested in airway hyperresponsiveness or detailed measurements of respiratory mechanics to read it. Click the book cover image for full details.

1Edited by Irving C. Allen, Mouse Models of Allergic Disease, Methods and Protocols.

GET THE BOOK FOR FREE

We are proud of this contribution and want to offer the possibility to the 10 first readers of this blog to get a free copy of this book. To enter the contest, simply e-mail us your name, organization name and mailing address at connect@scireq.com.

Wednesday, June 26, 2013

OUR FIRST VISUAL SCIENTIFIC PUBLICATION FEATURING THE FLEXIVENT

We are pleased to announce the publication of our first video article in the Journal of Visualized Experiments (JoVE). "[...] JoVE is a peer reviewed, PubMed indexed journal devoted to the publication of biological, medical, chemical and physical research in a video format."1

The article, which was produced in collaboration with the Meakins-Christie Laboratories of McGill University, illustrates and describes the steps to perform forced oscillation measurements in mice using the flexiVent. It includes the procedure to adequately prepare the system, tracheotomize, cannulate and mechanically ventilate a mouse, as well as to record lung function measurements. In addition, typical results at baseline and following aerosolized methacholine challenges are presented and discussed.

We invite you to watch the video and to read the article for additional details.

Evaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique

1JoVE - Peer Reviewed Scientific Video Journal - Methods and Protocols MyJoVE Corp. 2006-2013. < http://www.jove.com/about >.

Tuesday, June 4, 2013

Thank you for coming by our booth at ATS

We have been attending ATS for over 15 years and this year our team was present again to demonstrate our products and discuss with exhibit hall visitors. We were very pleased to see familiar faces from all over the world but also met many new researchers and scientists. We made the most out of our time in Philadelphia by presenting two posters and hosting the Breakfast Symposium: Refining the Dose Response while also attending sessions.

If you didn't get the chance to stop by our posters, please take a look by clicking on the title below to download each one.

Mechanical Test Load Comparative Study of Three FlexiVent System Configurations

Raised-Volume Low Frequency Forced Oscillation Measurements Of Respiratory Mechanics In Conscious And Anaesthetized Mice

A big thank you to the show organizers and everyone we met. We look forward to continuing the conversation!


Thursday, May 16, 2013

Come by our booth at ATS 2013

This year, at ATS, we have a lot of news to share with attendees. At booth 524, we will be demonstration our flexiVent FX system with our multi-subject extension (MSX) alongside our inExpose inhalation exposure system. You can look forward to learning more about our new dose response capabilities and other key features from our latest flexiWare 7.5 software.

Attendees can also be the first to watch our new JoVE video called Evaluation of Respiratory System Mechanics in Mice using the Forced Oscillation Technique. You can view the video in full by clicking here.

Posters

We are presenting two posters at ATS 2013, both during the same session on Sunday May 19th.

A1952 - Mechanical Test Load Comparative Study of Three flexiVent System Configurations
Poster Board Number: B38
Viewing Time: 10:45-12:30

A1957 - Raised-Volume Low Frequency Forced Oscillation Measurements Of Respiratory Mechanics In Conscious And Anaesthetized Mice
Poster Board Number: B43
Viewing Time: 10:45-12:30

Our Senior Scientist Dr. Annette Robichaud and flexiVent Product Manager Liah Fereydoonzad will both be present to discuss these findings.

Exhibit information

Pennsylvania Convention Center
Booth: 524

Exhibit hours:
Sunday, May 18 10am - 4pm
Monday, May 19 10:30am - 3pm
Tuesday, May 21 10:30am - 3pm

Breakfast Symposium

Don't miss our Breakfast Symposium on Tuesday May 21st at 7am. Complimentary continental breakfast will be served while our team presents the latest flexiVent developments. Click here to read more and register for this event.

Monday, May 13, 2013

New in flexiWare 7.5: Automated Dose Responses

Following our Software Release: flexiWare 7.5 blog posting, we received many requests for a software demo. In response, we held and recorded a webinar on May 7th, 2013. The webinar featured flexiWare 7.5's automated dose response functionality to show how this adds speed and efficiency to experimentation sessions. In addition, we also showcased the following features:

  • Support for our multi-subject extension (MSX)
  • Pressure controlled ventilation
  • Delivered volume during ventilation
  • Extended data export

This video is now available for your viewing.

For any questions, you can contact our team toll free at 1.877.572.4737 or by emailing us at techsupport@scireq.com

Thursday, May 9, 2013

SCIREQ Breakfast Symposium: Refining the Dose Response

We would like to invite you to join us for a Breakfast Symposium during ATS at the convention center’s adjoining hotel. The agenda will include the three presentations listed below, followed by an opportunity for personal discussions with members of our team. Our program will be timed such that attendees can conveniently reach the convention center for scientific sessions starting at 8:15.

DATE: Tuesday, May 21, 2013
TIME: 7 am – 8am (doors open at 6:45 am)
LOCATION: Philadelphia Marriott Downtown Hotel
Independance Room on the 3rd floor
1201 Market Street

Continental breakfast will be provided.
Please r.s.v.p. through the online registration form, by email at events@scireq.com or by calling us toll free at 1.877.572.4737.

Presentation schedule:

Refining the Dose Response: What's on Your Axis?
by Thomas F. Schuessler, PhD
New tools and concepts introduced in flexiWare 7.5 dramatically accelerate dose response studies, enhance group separation and improve the comparability of results across studies.

Refining the Dose Response: MSX = flexiVent4
by Liah Fereydonzad, BEng
Dose response studies done with the new flexiVent Multi-Subject extension (MSX) exponentially improve study design while allowing incredibly fast and efficient experimentation.

Refining the Dose Response: Towards Improving AHR Assessment
by Annette Robichaud, PhD
Nebulization protocols defined through careful understanding of the parameters not only improve AHR outcomes, but ensure data quality and reproducible aerosol challenges.

Friday, April 26, 2013

Boston events were a great success!

Our SCIREQ team was in Boston the week of April 21st exhibiting at Experimental Biology and hosting our very own flexiVent User Group Meeting. Both events were a great success as we were able to meet many new people and spend some quality time with our customers.

flexiVent User Group Meeting

We had over 15 flexiVent users join us on April 24th to discuss new flexiVent FX developments, new software features, frequently asked questions and even hear from select users on their current research. It was a great opportunity to meet new users and catch up with our flexiVent veterans.

Thank you to everyone who attended.

Keep an eye out for our next User Group Meeting in your area! We will be holding this event on a regular basis and would like your input if you are interest in having one in your area.

Thursday, April 18, 2013

Boston meetings to proceed as scheduled

All of us at SCIREQ would like to express our shock and horror at the atrocious events that took place at the Boston Marathon last Monday. Our hearts go out to the victims, their families and all those affected.

Experimental Biology

As per the information currently available to us, the exhibit at the Experimental Biology conference is set to proceed as scheduled. Further information can be found on the EB website.

The exhibit is located at the Boston Convention and Exhibition Center and is open April 21 to 23 from 9 am to 4 pm. Our SCIREQ team will be happy to welcome you at booth #446.

flexiVent User Group Meeting

The flexiVent User Group Meeting is scheduled for Wednesday, April 24, at the Westin Copley Plaza hotel. We have confirmed the continued availability and security of this venue with the hotel staff, therefore this meeting will also proceed as scheduled.

We understand that the proximity of our venue to the site of the attacks may cause discomfort to some of our attendees. However, after thorough consideration, we feel that the meeting should go ahead at this site as we refuse, whenever possible, to allow such events to change the way we live our lives. We hope that our attendees and clients agree with this choice, and that attendance at the User Group Meeting will be unattenuated.

For further information about the User Group Meeting, please refer to this earlier posting. To register, please fill in our online form.

We look forward to seeing you in Boston!

Friday, April 5, 2013

Visit us at CRC in Quebec City

If you are going to attend the Canadian Respiratory Conference in Quebec City from April 11 to 13, we invite you to come by the exhibits to talk to us and learn more about the latest flexiVent FX and inExpose developments. We will be sharing booth T7 with our sister company, THORASYS Thoracic Medical Systems Inc., makers of the tremoFlo Airwave Oscillometry System (AOS) to measure lung function without patient effort.

Canadian Respiratory Conference 2013
Quebec City Convention Center
April 11 - 13, 2013
Booth T7

Tuesday, April 2, 2013

Software release: flexiWare 7.5

SCIREQ is proud to announce the release of flexiWare 7.5, the latest version of our Study Management and Experiment Control Software. flexiWare 7.5 is a major upgrade that adds several new and exciting features to the software.

Dose Response

Our latest software allows flexiVent users to rapidly generate dose response graphs as well as customizable pre/post graphs directly within the flexiWare software. This enables a visualization of differences between study groups virtually in real time as the study progresses, and it tremendously reduces the time required for post-processing and reporting.

Moreover, the new flexiWare 7.5 allows plotting responses to inhaled challenges against an estimate of the delivered (i.e. inhaled) drug dose rather than concentration of drug in the nebulizer. We will soon issue more details on this significant, important refinement for dose response studies involving aerosols .

Multi-Subject Extension Support

flexiWare 7.5 now fully supports the new flexiVent multi-subject extension (MSX) that permits studying up to four subjects simultaneously with a single flexiVent FX system. The software now seamlessly adapts ventilation and perturbation scaling as subjects are added or removed from the system, and new calibration methods and analyzers have been added to support the assessment of lung mechanics using transfer impedance.

Ventilation Enhancements

flexiWare 7.5 also introduces a number of enhancements to the control of mechanical ventilation for flexiVent users. We have added Pressure-Controlled Ventilation (PCV) as a new mode of ventilation that, when used with the MSX, allows standardization the inspiratory pressure across parallel subjects. For single-subject configurations, the software now offers a feature to control the delivered volume when using volume controlled ventilation patterns. This algorithm accounts for gas compression within the ventilator circuit to ensure that the subject is receiving the desired tidal volume with the best possible accuracy.

HOW DO YOU UPGRADE?

If your current flexiWare installation is covered under our Complete Care program, our Technical Support team will be happy to assist you in downloading and installing your free upgrade. Otherwise, please contact our sales team at sales@scireq.com for further details and pricing information.


flexiVent FX with MSX extension

Tuesday, March 26, 2013

Coming soon: flexiWare 7.5

We are pleased to announce the upcoming release of flexiWare 7.5 which will greatly facilitate your dose response studies as well as supporting our new multi-subject extension (MSX). More details on the new features of flexiWare 7.5 to follow shortly on this blog.

Sunday, March 24, 2013

Join us in a discussion about the flexiVent

SCIREQ is hosting a flexiVent User Group Meeting Wednesday, April 24, 2013 following the Experimental Biology conference in Boston. Join our team for a day of scientific presentations and discussions to learn more about the flexiVent’s capabilities and its applications and share your feedback with other users. We look forward to your participation at this event.

Discussion sessions during the meeting will include:

  • flexiVent FX: overview, functionality and applications
  • Refining the Dose Response: What’s on Your Axis?
  • Introduction to the new Multi-Subject Extension (MSX)
  • Product demonstration
  • User presentations
  • Frequently asked questions

We will have the flexiVent FX and the MSX hardware extension all run on our latest flexiWare software (version 7.5) available for demonstration. If there are other topics you are interested in discussing, please let us know.

DATE: Wednesday, April 24, 2013
TIME: 9 am – 3 pm
LOCATION: Westin Copley Place Hotel, 10 Huntington Ave Boston, MA 02116

Please submit your registration by APRIL 8, 2013.

The easiest way to register is by filling out our online form. You can also contact us via email at events@scireq.com.

SPACE IS LIMITED | REGISTER TODAY!

Monday, March 18, 2013

SUCCESS AT SOT 2013

Our team just returned from the Society of Toxicology's 52nd Annual Meeting in San Antonio and it was a great success! We would like to thank everyone who visited the SCIREQ booth to discuss current and potential applications for our inExpose and flexiVent FX systems.

We look forward to a further discussion at Experimental Biology in Boston. Join us at booth #446 from April 21-23.

Wednesday, March 6, 2013

MEET WITH US AT SOT 2013 IN SAN ANTONIO

If your plans include attending the Society of Toxicology’s 52nd Annual Meeting, we invite you to visit us at booth 1128!  While in San Antonio, discuss your studies with our team, discover how our latest developments can impact your research and experience our systems for pre-clinical inhalation exposure and lung function measurements.
 

REFINING THE DOSE RESPONSE: STANDARDIZING THE CHALLENGE.

It is now easier than ever to compare inhaled challenges across studies thanks to new features available in our software. Nebulizer output may change over time and certainly varies from one substance to another.  To address the variability, we have suggested characterizing the nebulizer before and perhaps throughout experiments. The latest version of our software includes a characterization procedure that embeds the nebulizer output within the experiment data file. In addition, it uses the results of the characterization to calculate delivered dose following an inhaled challenge. The combination of these new features allows for further refinement in how the data are reported and interpreted and provides a level of standardization that was previously unavailable.

RESPIRATORY MECHANICS MEASUREMENTS IN CONSCIOUS DOGS AND PRIMATES

Following the preview available last fall at the SPS conference in Phoenix, view and discuss results from our collaboration with Dr. Simon Authier of CiToxLAB that aimed to test a novel approach (high frequency airwave oscillometry) to measure airway resistance non-invasively in conscious dogs and non-human primates  while recording conventional breathing parameters (e.g. tidal volume, respiratory rate).

Results are promising for applications in large animal toxicology studies as airwave oscillometry was well tolerated and more sensitive than some conventional respiratory parameters to drug-induced bronchoconstriction in non-human primates.

Learn more at the poster presentation on Monday, March 11th from 1:00 pm - 4:30 pm.
Session: Animal Models—Measurements and Validation
Abstract #757, Poster Board #636

PRODUCT DEMONSTRATIONS AND DISCUSSION AT OUR BOOTH

When it comes to inhalation exposure, SCIREQ offers the inExpose: a precise, bench top inhalation exposure system with customizable turn-key solutions from toxin generation to exhaust disposal, with real-time monitoring and control features, as well as computerized data acquisition and analysis. Its modular, compact form factor reduces direct and indirect costs, minimizes unintentional dilution and is ideal for use in a standard laboratory, without the need for a purpose-built facility.
Interested in respiratory mechanics? Come see our flexiVent with its Multi-Subject Extension (MSX). The flexiVent system has long been considered the gold standard for pre-clinical respiratory mechanics assessments. When used in combination with the MSX, it offers distinct study design advantages and greatly increases the efficiency of experimentation. The system will allow you to accelerate data collection and expediently carry out time-sensitive studies.

Visit our booth to discuss aerosol challenges or lung function measurements in conscious subjects, or for a demonstration of the inExpose or flexiVent. We look forward to speaking with you in San Antonio!
 

Exhibit hours:

Monday, March 11           9:00 AM - 4:30 PM

Tuesday, March 12          8:30 AM - 4:30 PM

Wednesday, March 13     8:30 AM - 4:30 PM