Monday, January 18, 2016

First 2016 flexiVent Publications

The New Year has just started and already an impressive number of publications featuring the flexiVent are available. Amongst these first 2016 publications, we are proud to highlight one by a Canadian group of researchers whose findings could prove to be useful to outline disease mechanisms or investigate new therapeutic avenues:

BIOSIGNATURE FOR AIRWAY INFLAMMATION IN A HOUSE DUST MITE-CHALLENGED MURINE MODEL OF ALLERGIC ASTHMA. - Hadeesha Piyadasa, Anthony Altieri, Sujata Basu, Jacquie Schwartz, Andrew J. Halayko, Neeloffer Mookherjee. Biology Open 2016 : doi: 10.1242/bio.014464

The flexiVent - An Invaluable Tool

The study describes a list of biomolecules pertaining to the allergen most frequently associated with human asthma, house-dust mite, in a preclinical model. It also includes relevant physiological endpoints such as airway hyperresponsiveness, a key feature of asthma, which, in this paper, was assessed using a detailed lung function measurement method exclusive to the flexiVent system. This approach is based on a multi-frequency forced oscillation evaluation of the respiratory system which permits the partitioning of the response into airway and tissue mechanics. A refined level of model characterization can thus be obtained for a deeper level of understanding.

Please contact us for more information on how to incorporate detailed lung function measurements into your studies.

View all publications

We invite you to click here and browse through over 1,500 publications featuring the flexiVent.

Author for correspondence

Dr. Neeloffer Mookherjee,